Article ID Journal Published Year Pages File Type
5815237 Neuropharmacology 2013 8 Pages PDF
Abstract
► COX-2 inhibition decreased cell death following OGD in vitro and in vivo stroke. ► Activation of the EP4 receptor showed comparable protection in the same models. ► Targeting pathways downstream of COX-2 avoids side effects of COX-2 inhibitors. ► Prostaglandin receptor signalling is a potential therapeutic target for stroke.
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