| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5815269 | Neuropharmacology | 2012 | 11 Pages |
Abstract
⺠Problematic gambling behaviour is associated with poor decision-making in humans. ⺠l-tryptophan deficient diet was used in rats to reduce 5-HT synthesis during 45 days. ⺠5-HT depleted rats did not improve their choice for a best long-term payoff in rIGT. ⺠Low 5-HT elicits risk-proneness (sub-optimal attraction towards binge reward) in rPDT. ⺠Relation between individual rIGT versus rPDT performance was disrupted by 5-HT depletion.
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Authors
S. Koot, F. Zoratto, T. Cassano, R. Colangeli, G. Laviola, R. van den Bos, W. Adriani,