Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5815283 | Neuropharmacology | 2012 | 13 Pages |
Abstract
⺠The effects of dopamine D1 & D2 antagonists were examined in the forced swimming test. ⺠D1 antagonism resulted in a direct reduction of climbing, the most effortful response. ⺠D2 antagonism induced persistently high levels of climbing up to the end of the session. ⺠D1 receptors might be involved in behavioural activation and response effort allocation. ⺠D2 receptors might be involved in the evaluation of response efficacy.
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Authors
Paolo S. D'Aquila, Adriana Galistu,