Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5815335 | Neuropharmacology | 2013 | 8 Pages |
Abstract
⺠A structure-based drug design yielded a new class of modulator of AMPA receptors. ⺠JAMI1001A binds in the solvent accessible pocket between AMPA receptor dimers. ⺠JAMI1001A alters desensitization and deactivation of flip and flop isoforms of GluA2.
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Authors
Jonathan E. Harms, Morris Benveniste, John K.F. Maclean, Kathryn M. Partin, Craig Jamieson,