Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5815380 | Neuropharmacology | 2013 | 10 Pages |
Abstract
⺠Egis-11150 is a candidate antipsychotic effective in preclinical psychosis models. ⺠Egis-11150 shows robust procognitive potency in four different animal models. ⺠Inhibitor of adrenergic alpha1, alpha2c, 5-HT2a, 5HT7 receptors with high affinity. ⺠Relatively selective blocker of adrenergic alpha2c over adrenergic alpha2a receptors.
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Authors
István Gacsályi, Katalin Nagy, Katalin Pallagi, György Lévay, László G. Jr., Krisztina Móricz, Szabolcs Kertész, Péter Varga, József Haller, Gábor Gigler, Gábor Szénási, József Barkóczy, Judit BÃró, Michael Spedding, Ferenc A. Antoni,