Article ID Journal Published Year Pages File Type
5815399 Neuropharmacology 2013 8 Pages PDF
Abstract
► We compared the behavior of nifedipine-treated wildtype and NK1R−/− mice in the 5-CSRTT. ► Impulsivity and perseveration were reduced and inattentiveness was increased in both genotypes. ► Nifedipine was more potent in wildtypes than NK1R−/− mice. ► Accuracy was unaffected in either genotype. ► Functional coupling between NK1R and L-type channels affects cognitive performance.
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