| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5815501 | Neuropharmacology | 2012 | 10 Pages |
Abstract
⺠Non-motor features of PD represent important challenges in the clinical management of PD. ⺠We reviewed clinical and experimental findings of anxiety in PD. ⺠Anxiety disorders are often under-diagnosed and under-treated in PD patients. ⺠The search for new agents for the anxiety relief in PD is necessary. ⺠We hope to motivate clinicians and researchers to change this scenario.
Keywords
TCAsMPTPNMDAVTA5-HT5-HIAASSRIs5-HT1AMFBDOPACmGluRsMAO-BVMAT-2RCTsICDS5-HT2A/2Cserotonin receptor type 1ABLA6-OHDADSMEPM6-Hydroxydopamine1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine3,4-dihydroxyphenylacetic acid5-Hydroxyindoleacetic acidSNpcRandomized controlled trialsImpulse control disordersgamma-aminobutyric acidAnxietyelevated plus mazemedial forebrain bundleBenzodiazepinesParkinson’s diseaseParkinson's diseasesubstantia nigrasubstantia nigra pars compactatyrosine hydroxylasetricyclic antidepressantsCNSDopamineDiagnostic and Statistical Manual of Mental DisordersSerotonincentral nervous systemAnimal modelsReviewClinical studiesselective serotonin reuptake inhibitorsmonoamine oxidase BVesicular monoamine transporter-2ventral tegmental areanoradrenalinebasolateral nucleus of the amygdalahomovanillic acidHVAHPLCGABAN-methyl-d-aspartate receptorMetabotropic glutamate receptors
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Authors
Rui D.S. Prediger, Filipe C. Matheus, Marcelo L. Schwarzbold, Marcelo M.S. Lima, Maria A.B.F. Vital,