Article ID Journal Published Year Pages File Type
5815615 Neuropharmacology 2012 8 Pages PDF
Abstract
► α7 nAchR activation did not inhibit established colonic inflammation induced by DSS. ► α7 nAchR activation inhibited referred hyperalgesia caused by colonic inflammation. ► α7 nAchR agonists might be used to treat pain and discomfort associated with IBDs.
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Life Sciences Neuroscience Behavioral Neuroscience
Preview
Activation of the alpha-7 nicotinic acetylcholine receptor (α7 nAchR) reverses referred mechanical hyperalgesia induced by colonic inflammation in mice
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