| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5815619 | Neuropharmacology | 2012 | 5 Pages |
Abstract
⺠Eker rats (tuberous sclerosis-autism model) have elevated cerebral metabolism. ⺠This is not related to high basal AMPA receptor activity. ⺠We tested whether AMPA would increase cerebral O2 consumption in Eker rats. ⺠AMPA increased cortical O2 consumption in controls, but not in Eker rats. ⺠This was correlated with reduced AMPA receptor protein levels in the Eker rat.
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Authors
Harvey R. Weiss, Xia Liu, Parneet Grewal, Oak Z. Chi,