| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5815622 | Neuropharmacology | 2012 | 12 Pages |
Abstract
⺠The present study examined the effects of EF on the development of EAE in rats and elucidated its underlying mechanisms. ⺠Intragastrical administration of EF (20 and 60 mg/kg) significantly reduced clinical score of neurological deficit in EAE rats. ⺠The effects of EF may involve reducing neuroinflammation and enhancing myelination and neurotrophins. ⺠Our findings suggest that EF may be useful for the treatment of multiple sclerosis.
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Behavioral Neuroscience
Authors
Lin-Lin Yin, Li-Li Lin, Lan Zhang, Lin Li,