| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5815662 | Neuropharmacology | 2012 | 13 Pages |
Abstract
⺠SERM-beta1 and 2 are selective, non-proliferative, brain penetrant ERβ modulators. ⺠SERM-beta compounds modulated the levels of TPH1 mRNA and PR protein in raphe nuclei. ⺠SERM-beta compounds promoted neurogenesis and showed antidepressant activity in vivo.
Related Topics
Life Sciences
Neuroscience
Behavioral Neuroscience
Authors
J.A. Clark, S. Alves, C. Gundlah, B. Rocha, E.T. Birzin, S.-J. Cai, R. Flick, E. Hayes, K. Ho, S. Warrier, L. Pai, J. Yudkovitz, R. Fleischer, L. Colwell, S. Li, H. Wilkinson, J. Schaeffer, R. Wilkening, S.P. Rohrer,