| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5815667 | Neuropharmacology | 2012 | 10 Pages |
Abstract
⺠Depletion of N.Acc. cholinergic neurons impaired performance in a delayed alternation task. ⺠These lesions markedly reduced stress-induced in vivo prefrontal cortical DA activation. ⺠In lesioned rats, cognitive impairments correlated significantly with cortical DA deficits. ⺠N.Acc. cholinergic depletion affects mesocorticolimbic function.
Keywords
5-HT5-HIAAPFCDOPACVTA3,4-dihydroxyphenylacetic acid5-Hydroxyindoleacetic acidVentral striatumAscorbic acidAChAcetylcholineSchizophreniaImmunohistochemistrytyrosine hydroxylaseDopaminesaporinprefrontal cortexAnimal modelventral tegmental areanorepinephrineNucleus accumbensChATcholine acetyltransferase
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Authors
François Laplante, Zi-Wei Zhang, Frédéric Huppé-Gourgues, Marc M. Dufresne, Elvire Vaucher, Ron M. Sullivan,