| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5815672 | Neuropharmacology | 2012 | 14 Pages |
Abstract
⺠5-HT7 receptor agonists reduced mechanical hyperalgesia in sciatic nerve-ligated rats. ⺠Intrathecal bicuculline blocked 5-HT7R-mediated antihyperalgesia in neuropathic rats. ⺠5-HT7R-mediated antihyperalgesia is unaffected by spinal opioid receptors blockade. ⺠Both spinal and supraspinal processes contributed to 5-HT7R-mediated antihyperalgesia.
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Authors
Florent Viguier, Benoît Michot, Valérie Kayser, Jean-François Bernard, José-Miguel Vela, Michel Hamon, Sylvie Bourgoin,