Article ID Journal Published Year Pages File Type
5815700 Neuropharmacology 2011 7 Pages PDF
Abstract
► Anti-cancer drugs (methotrexate + 5-fluouracil) caused cognitive impairment in mice. ► Drugs affected hippocampal memory and executive function under frontal-lobe control. ► Both types of cognitive impairment significantly reduced by donepezil treatment.
Keywords
Related Topics
Life Sciences Neuroscience Behavioral Neuroscience
Preview
Donepezil reduces cognitive impairment associated with anti-cancer drugs in a mouse model
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