Article ID Journal Published Year Pages File Type
5815723 Neuropharmacology 2011 9 Pages PDF
Abstract
► Dysbindin-1A overexpression in hippocampal neurons causes NMDAR hypofunction and blocks LTP. ► Surface NR1 subunit expression is decreased. ► Inhibition of endocytosis reverses the deficit in NMDAR signaling.
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Related Topics
Life Sciences Neuroscience Behavioral Neuroscience
Preview
Increased expression of dysbindin-1A leads to a selective deficit in NMDA receptor signaling in the hippocampus
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