Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5815763 | Neuropharmacology | 2012 | 10 Pages |
Abstract
⺠Hippocampal neurons cultured from CB1 KO mice are insensitive to cannabinoids. ⺠CB2 expressed in these neurons restored sensitivity to exo- and endo-cannabinoids. ⺠CB2 likely inhibit calcium channels to suppress synaptic transmission. ⺠Ongoing 2-arachidonoylglycerol production tonically activated transfected CB2.
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Authors
Brady K. Atwood, Alex Straiker, Ken Mackie,