| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5815787 | Neuropharmacology | 2012 | 10 Pages |
Abstract
⺠Noradrenergic antidepressants selectively increase DA function in PFC but not in NAc. ⺠The combination of reboxetine and mirtazapine selectively increases DA and NE in mPFC. ⺠This evokes antidepressant-like effects (FST) and increases c-fos and BDNF in HPC. ⺠Citalopram pre-treatment does not interfere with the effects of these drugs. ⺠Potentially useful in SSRI-resistant depression and negative symptoms in schizophrenia.
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Authors
Mercè Masana, Anna Castañé, Noemà Santana, AnalÃa Bortolozzi, Francesc Artigas,