| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5815825 | Neuropharmacology | 2012 | 12 Pages |
Abstract
⺠Glutamate uptake inhibition by PJ-34 induced persistent synchronous discharges. ⺠Strong, glutamate-mediated discharges remained even after washout of PJ-34. ⺠No histological damage was detected 24 h later. ⺠Fictive locomotion and synaptic reflexes were not impaired. ⺠Large network excitation was compensated by downsizing synaptic transmission.
Keywords
D-APV5-HTCCFmotoneuronsFFT5-hydroxytryptamineDAPImGluREAAT24′,6-diamidino-2-phenylindole6-Cyano-7-nitroquinoxaline-2,3-dioneD-(−)-2-amino-5-phosphonopentanoic acidexcitotoxicityFast Fourier transformanalysis of varianceANOVALeftfictive locomotionExcitatory amino acid transporter 2dorsal rootCNQXlumbarGABAgamma-amino butyric acidMetabotropic glutamate receptor
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Authors
Sara Ebrahimi Nasrabady, Anujaianthi Kuzhandaivel, Athena Akrami, Elena Bianchetti, Marco Milanese, Giambattista Bonanno, Andrea Nistri,