| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5815830 | Neuropharmacology | 2012 | 9 Pages |
Abstract
⺠TCN 201 is a potent and selective GluN1/GluN2A NMDAR antagonist. ⺠TCN 201 antagonism is dependent on the GluN1-agonist concentration. âºÂ TCN 201 antagonism is independent on the GluN2-agonist concentration. ⺠TCN 201 blocks GluN2A-containing NMDARs in a non-competitive manner. ⺠TCN 201 allows pharmacological identification of native GluN2 A-containing NMDAR populations.
Related Topics
Life Sciences
Neuroscience
Behavioral Neuroscience
Authors
S. Edman, S. McKay, L.J. MacDonald, M. Samadi, M.R. Livesey, G.E. Hardingham, D.J.A. Wyllie,