Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5815857 | Neuropharmacology | 2012 | 11 Pages |
Abstract
⺠Inhibition of PDE4B and GSK-3 in sub-threshold doses elicited antipsychotic effect. ⺠DISC1-Q31L decreased PDE4B activity and increased sensitivity to GSK-3 blocker. ⺠PDE4B and GSK-3 synergistically interact with each other via DISC1.
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Authors
Tatiana V. Lipina, Min Wang, Fang Liu, John C. Roder,