The viral theory of schizophrenia revisited: Abnormal placental gene expression and structural changes with lack of evidence for H1N1 viral presence in placentae of infected mice or brains of exposed offspring

► Infection at E7 altered gene expression in the placentae of infected dams. ► Infection at E7 altered gene expression in PFC and hippocampus of exposed offspring. ► mRNA for viral genes was not found in placentae, PFC, or hippocampus. ► Infection at E7 caused structural changes in the placenta. ► Infection at E7 had little effect on brain structure of exposed offspring.