Article ID Journal Published Year Pages File Type
5815880 Neuropharmacology 2012 10 Pages PDF
Abstract
► Antipsychotic drugs (APD) have little effect on negative and cognitive symptoms in schizophrenia. ► There appear to be few major differences between first and second generation APDs. ► Novel APD strategies focus on serotonin, glutamate, acetylcholine and PDE10. ► In addition, novel cognitive enhancer (5-HT6, H3) are being evaluated. ► A major breakthrough in therapy has yet to be identified.
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Life Sciences Neuroscience Behavioral Neuroscience
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