Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5815894 | Neuropharmacology | 2012 | 10 Pages |
Abstract
⺠Repeated PCP administration increased glutamate release in the PFC of rats. ⺠The repeated PCP-induced increase in PFC glutamate was blunted compared with that seen after a single PCP injection. ⺠Repeated PCP administration decreased markers of GABA function in the PFC. ⺠Clozapine attenuated the PCP-induced changes in glutamate and GABA function.
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Authors
Nurith Amitai, Ronald Kuczenski, M. Margarita Behrens, Athina Markou,