Article ID Journal Published Year Pages File Type
5815894 Neuropharmacology 2012 10 Pages PDF
Abstract
► Repeated PCP administration increased glutamate release in the PFC of rats. ► The repeated PCP-induced increase in PFC glutamate was blunted compared with that seen after a single PCP injection. ► Repeated PCP administration decreased markers of GABA function in the PFC. ► Clozapine attenuated the PCP-induced changes in glutamate and GABA function.
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Life Sciences Neuroscience Behavioral Neuroscience
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