Article ID Journal Published Year Pages File Type
5815949 Neuropharmacology 2011 13 Pages PDF
Abstract
► Depression is the most common neuropsychiatric co-morbidity in Parkinson's disease. ► Low 5-HT and altered basal ganglia activity may be critical to develop depression. ► STN DBS has shown to inhibit 5-HT neurotransmission in animal models. ► Inhibited 5-HT transmission may underlie STN DBS depressive-like side effects.
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Life Sciences Neuroscience Behavioral Neuroscience
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