Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5815949 | Neuropharmacology | 2011 | 13 Pages |
Abstract
⺠Depression is the most common neuropsychiatric co-morbidity in Parkinson's disease. ⺠Low 5-HT and altered basal ganglia activity may be critical to develop depression. ⺠STN DBS has shown to inhibit 5-HT neurotransmission in animal models. ⺠Inhibited 5-HT transmission may underlie STN DBS depressive-like side effects.
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Authors
Sonny K.H. Tan, Henrike Hartung, Trevor Sharp, Yasin Temel,