| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5815958 | Neuropharmacology | 2011 | 7 Pages |
Abstract
⺠Nicotine demonstrated pronounced behavioural sensitisation to its stimulant actions. ⺠The 5-HT6 receptor antagonist SB-271046 reduced the development and expression of nicotine sensitisation. ⺠These data suggest the utility of 5-HT6 receptor antagonists for reducing the effects of nicotine. ⺠Together, these data suggest that more detailed studies with 5-HT6 antagonists to reduce addiction are warrented.
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Authors
N.M.W.J. de Bruin, B.M. Kloeze, A.C. McCreary,