Impulsive action induced by amphetamine, cocaine and MK801 is reduced by 5-HT2C receptor stimulation and 5-HT2A receptor blockade

► Amphetamine, cocaine and MK801 increased impulsivity in the 5-CSRT test. ► The 5-HT2C receptor agonist Ro60-0175 reduced this drug-induced impulsive action. ► The 5-HT2A receptor antagonist M100907 reduced this drug-induced impulsive action. ► These drugs did not impair attention, motivation or motor aspects of performance.