| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5816239 | Neuropharmacology | 2008 | 7 Pages |
Abstract
These data suggest that, in the hippocampus, WIN 55,212-2 reduces glutamate release from Schaffer collaterals solely via CB1Rs in the nM concentration range, whereas in μM concentrations, WIN 55,212-2 suppresses excitatory transmission, in addition to activation of CB1Rs, by directly blocking N-type voltage-gated Ca2+ channels independent of CB1Rs.
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Authors
Beáta Németh, Catherine Ledent, Tamás F. Freund, Norbert Hájos,