Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5821857 | Antiviral Research | 2016 | 10 Pages |
Abstract
This was the first nonhuman primate study of influenza and bacterial co-infection where high-resolution computed tomography scanning of the lungs was used to quantitatively assess pneumonia over the course of illness and where hypoxemia was correlated with pneumonia severity. With additional validation this model may serve as a pathway for regulatory approval of vaccines and therapeutics for the prevention and treatment of severe influenza pneumonia.
Related Topics
Life Sciences
Immunology and Microbiology
Virology
Authors
Daniel S. Chertow, Jason Kindrachuk, Zong-Mei Sheng, Lindsey M. Pujanauski, Kurt Cooper, Daniel Nogee, Marisa St. Claire, Jeffrey Solomon, Donna Perry, Philip Sayre, Krisztina B. Janosko, Matthew G. Lackemeyer, Jordan K. Bohannon, John C. Kash,