Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5822269 | Antiviral Research | 2014 | 8 Pages |
Abstract
The results demonstrated that anti-papilloma treatments with topical CDV were greatly enhanced when formulated versus unformulated. Best results were obtained with CDV formulated in cremophor, then in Carbomer 940, and then in DMSO. Further studies indicated that effective formulations led to complete cures of papillomas at dilutions less than 0.3% CDV. These studies together with previous observations demonstrated that unformulated CDV under the same treatment regime required doses of 2% to achieve cures demonstrating that much less compound can be used when properly formulated.
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Authors
Neil D. Christensen, Nancy M. Cladel, Jiafen Hu, Karla K. Balogh,