| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5822468 | Antiviral Research | 2012 | 11 Pages |
Abstract
⺠NP-encoding vRNA (NP-vRNA) of H9N2 virus is targeted for degradation by antibody. ⺠NP25 antibody selectively hydrolyzes a 18-nt ssDNA derived from the NP-vRNA. ⺠The expression of NP25 does not show any significant cytotoxicity to the host cells. ⺠NP25 potently inhibits the replication of H9N2 virus in the stable cell lines. ⺠NP25 selectively hydrolyzes the targeted NP-vRNA in the stable cell lines.
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Authors
Aeyung Kim, Ja-Yeong Lee, Sung June Byun, Myung-Hee Kwon, Yong-Sung Kim,