Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5822484 | Antiviral Research | 2013 | 11 Pages |
Abstract
⺠17mer Phosphorothioate modified ODN (tS-ODN) binding HCV5â²NCR inhibit HCV translation. ⺠Conjugation of tS-ODN to taurocholate increases selective ODN uptake by hepatocytes. ⺠Taurocholate conjugated tS-ODNs enhance inhibition of HCV translation in liver cells.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Virology
Authors
Maria A. González-Carmona, Maria Quasdorff, Annabelle Vogt, Anja Tamke, Yildiz Yildiz, Per Hoffmann, Thomas Lehmann, Ralf Bartenschlager, Joachim W. Engels, Gerd A. Kullak-Ublick, Tilman Sauerbruch, Wolfgang H. Caselmann,