Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5822494 | Antiviral Research | 2013 | 7 Pages |
Abstract
⺠Silencing of SOCS1 by shRNA increased the anti-HCV effect of IFN. ⺠Overexpression of SOCS1 prior to IFN treatment inhibited JAK-STAT signaling pathway. ⺠SOCS1 negatively regulates IFN signaling during HCV treatment.
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Authors
Run-Xuan Shao, Leiliang Zhang, Zhi Hong, Kaku Goto, Du Cheng, Wen-Chi Chen, Nikolaus Jilg, Kattareeya Kumthip, Dahlene N. Fusco, Lee F. Peng, Raymond T. Chung,