Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5822501 | Antiviral Research | 2013 | 7 Pages |
Abstract
⺠ASP2151 is a helicase-primase inhibitor against Alphaherpesvirinae viruses. ⺠Combination effect of ASP2151 with existing antiherpes agents was studied. ⺠ASP2151 combined with ACV showed synergistic effect against HSV-1, HSV-2, and VZV. ⺠ASP2151 combined with VACV was more potent than each monotherapy in mouse model.
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Authors
Koji Chono, Kiyomitsu Katsumata, Hiroshi Suzuki, Kimiyasu Shiraki,