Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5822510 | Antiviral Research | 2013 | 7 Pages |
Abstract
⺠Curing HIV infection must address the pool of cells that harbor latent virus. ⺠Gene therapy strategies may be required to eradicate infected cells. ⺠Specific endonucleases can directly target integrated HIV proviral DNA. ⺠Tre-recombinase can remove integrated HIV-1 from infected cells. ⺠A Tre-recombinase recognizing most HIV-1 subtypes should be developed.
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Authors
Frank Buchholz, Joachim Hauber,