Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5822518 | Antiviral Research | 2012 | 11 Pages |
Abstract
⺠Lopinavir/ritonavir causes lipodystrophy and insulin resistance in mice. ⺠Lopinavir/ritonavir impairs cognition and increases depressive behavior. ⺠Lopinavir/ritonavir induces cerebrovascular injury and synapse loss. ⺠Cognitive impairment correlates with lipodystrophy and insulin resistance.
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Authors
Sunita Gupta, Alecia G. Knight, Boriss Y. Losso, Donald K. Ingram, Jeffrey N. Keller, Annadora J. Bruce-Keller,