Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5822537 | Antiviral Research | 2011 | 9 Pages |
Abstract
⺠We demonstrated the virucidal activity of NVC-422 against adenovirus type 5. ⺠In vitro assays show that NVC-422 has a good therapeutic index. ⺠The virucidal activity of NVC-422 is rapid with complete inactivation of Ad5 within 15 min. ⺠The virucidal activity of NVC-422 is due to its reacting with key viral proteins.
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Authors
Jungjoo Yoon, Andreas Jekle, Ramin Najafi, Francis Ruado, Meghan Zuck, Behzad Khosrovi, Bahram Memarzadeh, Dmitri Debabov, Lu Wang, Mark Anderson,