Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5822539 | Antiviral Research | 2011 | 5 Pages |
Abstract
⺠Mutations conferring resistance to VIRIP/VIR-353 do not appear in the fusion peptide of gp41. ⺠Resistance to VIRIP induced a change in virus replicative capacity. ⺠Mutations in gp120 and gp41 restored virus replicative capacity maintaining the resistant phenotype. ⺠There is a high genetic barrier for resistance to VIRIP and its analogues.
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Authors
Emmanuel González-Ortega, Ester Ballana, Roger Badia, Bonaventura Clotet, José A. Esté,