| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5822572 | Antiviral Research | 2012 | 8 Pages |
Abstract
⺠HBsAg genetic markers correlated with occult HBV D genotype infection in vivo were studied. ⺠Twenty HBsAg-mutations significantly correlated for the first time with OBI were found. ⺠They localized in the major HBV B-cell-epitope, and in HBsAg-capsid interaction region. ⺠They strongly affect, up to abrogate, HBsAg detection. ⺠Thus, they can affect full-reliability of diagnostic-assays for HBsAg-detection.
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Authors
Valentina Svicher, Valeria Cento, Martina Bernassola, Maria Neumann-Fraune, Formijn Van Hemert, Mengjie Chen, Romina Salpini, Chang Liu, Roberta Longo, Michela Visca, Sara Romano, Valeria Micheli, Ada Bertoli, Caterina Gori,