Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5822618 | Antiviral Research | 2013 | 8 Pages |
Abstract
⺠We synthesized five unnatural nucleoside analogs. ⺠Two analogs can efficiently inhibit WNV methyltransferase (MTase) activity. ⺠The anti-WNV MTase compounds did not inhibit human mRNA MTase. ⺠The mechanism of selectivity is different from what was reported previously.
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Authors
Hui Chen, Lihui Liu, Susan A. Jones, Nilesh Banavali, Jorden Kass, Zhong Li, Jing Zhang, Laura D. Kramer, Arun K. Ghosh, Hongmin Li,