| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5822620 | Antiviral Research | 2013 | 10 Pages |
Abstract
⺠We describe an efficient approach to generate antiviral single-domain antibodies. ⺠The activity of initially selected antibodies can be greatly increased by formatting. ⺠Described formatting procedure adds a trimerization domain to the antibody sequence. ⺠Formatted single-domain antibody can protect mice from influenza virus infection.
Keywords
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Immunology and Microbiology
Virology
Authors
Sergei V. Tillib, Tatiana I. Ivanova, Lev A. Vasilev, Marina V. Rutovskaya, Seda A. Saakyan, Irina Y. Gribova, Irina L. Tutykhina, Elena S. Sedova, Andrei A. Lysenko, Maxim M. Shmarov, Denis Y. Logunov, Boris S. Naroditsky, Alexander L. Gintsburg,