Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5822656 | Antiviral Research | 2012 | 9 Pages |
Abstract
⺠We construct an attenuated TE3L deficient vaccinia virus Tian Tan strain. ⺠Cell toxicity of the attenuated virus is significantly decreased. ⺠The in vivo virulence of the attenuated virus is reduced. ⺠The attenuated virus is a candidate vector with increased safety.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Virology
Authors
Yuhang Wang, Shifu Kan, Shouwen Du, Yanxin Qi, Jinhui Wang, Liming Liu, Huifan Ji, Dongyun He, Na Wu, Chang Li, Baorong Chi, Xiao Li, Ningyi Jin,