Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5822705 | Antiviral Research | 2012 | 17 Pages |
Abstract
⺠Characterized NS3 RNA helicase inhibitors synthesized from the dye primuline. ⺠Discovered that a subset of primuline derivatives also inhibit the NS3 protease. ⺠Showed that some primuline derivatives are also potent inhibitors of Dengue virus NS3. ⺠Found a primuline derivative active against the HCV subgenomic replicon.
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Authors
Jean Ndjomou, Rajesh Kolli, Sourav Mukherjee, William R. Shadrick, Alicia M. Hanson, Noreena L. Sweeney, Diana Bartczak, Kelin Li, Kevin J. Frankowski, Frank J. Schoenen, David N. Frick,