Article ID Journal Published Year Pages File Type
5822708 Antiviral Research 2012 9 Pages PDF
Abstract
► Ribavirin reduced phosphorylation of ERK and STAT1 but increased STAT3 phosphorylation. ► IFN-α regulated ERK and STAT3 synergistically with ribavirin but up-regulated expression and phosphorylation of STAT1. ► ERK and STAT pathways were down-regulated by ribavirin following HCVcc infection. ► Ribavirin decreased HCV RNA and protein expression levels.
Related Topics
Life Sciences Immunology and Microbiology Virology
Authors
, , , , ,