Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5822708 | Antiviral Research | 2012 | 9 Pages |
Abstract
⺠Ribavirin reduced phosphorylation of ERK and STAT1 but increased STAT3 phosphorylation. ⺠IFN-α regulated ERK and STAT3 synergistically with ribavirin but up-regulated expression and phosphorylation of STAT1. ⺠ERK and STAT pathways were down-regulated by ribavirin following HCVcc infection. ⺠Ribavirin decreased HCV RNA and protein expression levels.
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Authors
Lan-Juan Zhao, Wen Wang, Yuan Liu, Hao Ren, Zhong-Tian Qi,