Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5822715 | Antiviral Research | 2012 | 9 Pages |
Abstract
⺠U1 interference (U1i) molecules were designed to inhibit HIV-1 RNA. ⺠One U1i inhibitor revealed high potency in various transient transfection assays. ⺠This potency is due to a tandem target site in the HIV-1 RNA. ⺠U1i combined with a lentiviral gene therapy approach needs optimization.
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Authors
Stefanie A. Knoepfel, Amaya Abad, Xabi Abad, Puri Fortes, Ben Berkhout,