Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5824395 | Clinical Therapeutics | 2016 | 13 Pages |
Abstract
The communication of cell injury and death is a critical element in host defense and involves the repurposing of nuclear molecules as immune triggers. As such, the presence of extracellular nuclear material can serve as novel biomarkers for conditions involving cell injury and death. Targeting of these molecules may also represent an important new approach to therapy.
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Authors
Melinda MS, David S. MD, PhD,