Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5824747 | Clinical Therapeutics | 2015 | 6 Pages |
Abstract
Febuxostat could significantly reduce d-ROMs. However, BAP levels were also significantly reduced concurrently. No changes were observed in the BAP/d-ROMs ratios. This regulatory mechanism is believed to have counteracted changes in the in vivo oxidative stress balance caused by febuxostat administration.
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Authors
Toshiki MD, PhD, Mie MD, Kazuhiro MD, Sumie MT, Tadashi MT, Youichi MD, PhD,