Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5825211 | Clinical Therapeutics | 2015 | 14 Pages |
Abstract
CG100649 was well tolerated and demonstrated a whole blood concentration that is ~50 to 70 times higher than in plasma in these healthy subjects. CG100649 suppressed TXB2 and PGE2 at all 3 doses, and only the highest dose suppressed the urinary excretion of the urinary prostacyclin metabolite.
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Authors
Mi Jo MD, Hyeong-Seok MD, PhD, Seokjoon MD, PhD, Jin Ah MD, Yook-Hwan MD, Yo Han MD, Kyun-Seop MD, PhD,