Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5825583 | Clinical Therapeutics | 2014 | 16 Pages |
Abstract
Even when on antifungal therapy, invasive fungal infection will develop in 1 of 20 patients undergoing hematopoietic stem cell transplantation. There is evidence for the comparable effectiveness of different antifungal drugs used for prophylaxis. Fluconazole is the most widely studied agent, but micafungin might prove to be more effective. There is a relative paucity of studies for the newer azoles, although both voriconazole and posaconazole give proof of their comparative or higher effectiveness to fluconazole in single randomized studies.
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Authors
Panayiotis D. MD, PhD, Irene S. MD, PhD, Eleftherios MD, PhD, FIDSA,