Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5826184 | Current Opinion in Pharmacology | 2012 | 10 Pages |
Abstract
⺠Cigarette smoke causes oxidative stress in COPD. ⺠Antioxidants can modulate intracellular redox system. ⺠Thiols, enzyme mimetics, spin traps, and redox sensors are therapeutic agents. ⺠Lipid peroxidation and protein carbonylation inhibitors block oxidative processes. ⺠Antioxidants have pharmacological beneficial effects in management of COPD.
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Authors
Irfan Rahman, William MacNee,