| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5826194 | Current Opinion in Pharmacology | 2012 | 6 Pages |
Abstract
⺠Protease/antiprotease imbalance is one of the recognized causes of pulmonary emphysema in smokers and patients with AAT deficiency. ⺠Augmentation therapy with intravenous AAT reduces the progression of loss of lung density in patients with congenital emphysema. ⺠Optimization of intravenous regimen must be made on an individual basis based on the pharmacokinetics of infused AAT. ⺠The search for novel antiproteases that could potentially be used in smokers COPD is an ongoing field of intense research.
Related Topics
Life Sciences
Neuroscience
Cellular and Molecular Neuroscience
Authors
Marc Miravitlles,